- (informal)
upset and anxious, especially because of something bad that has happened to you in the past （因以前有过不幸遭遇）焦虑而紧张的 an extremely screwed-up kid 一个十分神经质的孩子
- (especially British English)
twisted into a ball 揉起来的；搓成一团的 a screwed-up tissue 揉成一团的纸巾
if your face or eyes are screwed-up, the muscles are tight, because you are worried, in pain, etc., or because the light is too bright （因担忧、疼痛或光线太强等）面部扭曲，眯起眼睛，皱着眉头